PRP can initiate a healing response and the first phase of healing involves inflammation. As a result, PRP may initially cause stiffness and mild swelling that can potentially last for up to one week. Anti-inflammatory medications are discouraged for up to two weeks after the procedure to allow for an adequate natural inflammatory response. Ice, acetaminophen (Tylenol), and prescribed pain medications can be used if necessary. Motion Activity involving the injured body without strengthening is encouraged. Physical therapy is encouraged following the treatment, depending on the nature of the injury.